Search results for "MESH: Semicarbazides"

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Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 deficiency reduces leukocyte infiltration into adipose tissue and favors fat deposi…

2009

1525-2191 (Electronic) Journal Article; Obesity is associated with low-grade inflammation and leukocyte infiltration in white adipose tissue (WAT) and is linked to diabetic complications. Semicarbazide-sensitive amine oxidase, also known as vascular adhesion protein-1 (SSAO/VAP-1), is a membrane protein that is highly expressed in adipocytes and is also present on the endothelial cell surface where it is involved in leukocyte extravasation. We studied fat deposition and leukocyte infiltration in WAT of mice with a null mutation in the amine oxidase copper-containing-3 (AOC3) gene encoding SSAO/VAP-1. Both epididymal and inguinal WATs were larger in 6-month-old AOC3-KO males than in age-matc…

MESH: SemicarbazidesAOC3Obesity/geneticsAdipose tissueMESH: Flow CytometryWhite adipose tissueInbred C57BLMESH: Mice KnockoutTransgenicMiceLeukocytesMESH: ObesityMESH: AnimalsMice KnockoutAmine oxidase (copper-containing)food and beveragesNatural killer T cellFlow CytometryLeukocyte extravasationSemicarbazidesCell Adhesion Molecules/*deficiency/*geneticsAdipose TissueMESH: Cell Adhesion MoleculesLeukocytes/*physiologyAmine Oxidase (Copper-Containing)medicine.symptomInfiltration (medical)MESH: Adipose Tissuemedicine.medical_specialtyMESH: Mice TransgenicKnockoutMice TransgenicInflammation[SDV.BC]Life Sciences [q-bio]/Cellular BiologyBiologyMESH: Monoamine OxidasePathology and Forensic MedicineMESH: LeukocytesMonoamine Oxidase/*deficiencyMESH: Mice Inbred C57BLInternal medicinemedicineAnimalsHumansObesityMonoamine OxidaseMESH: Mice[SDV.BC] Life Sciences [q-bio]/Cellular BiologyMESH: HumansAmine Oxidase (Copper-Containing)/*deficiency/*geneticsmedicine.diseaseAdipose Tissue/pathology/*physiologyMice Inbred C57BLEndocrinologyImmunologyMESH: Amine Oxidase (Copper-Containing)Semicarbazides/*pharmacologyCell Adhesion MoleculesRegular Articles
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